$312 Donated to date
When the Foundation was established in 1955, children with CF rarely lived long enough to attend elementary school. Due in large part to the Foundation's aggressive investments in innovative research and comprehensive care, many people with the disease can now expect to live into their 30s, 40s and beyond.In 1989, CF Foundation-supported scientists discovered the defective gene that causes cystic fibrosis — a monumental breakthrough on the road to a cure.The Foundation played an integral role in the development and FDA approval of five therapies that are now part of regular treatment regimens for many with CF. The Foundation has a robust pipeline of promising potential drugs that target the disease from every angle.
In 2012, the FDA approved the groundbreaking drug Kalydeco™, the first drug to treat the underlying cause of CF in a small group of people with the disease. The Foundation also is supporting research that may eventually treat the root cause of the disease in all people living with CF.
What You Need to Know
What Is Cystic Fibrosis?
Cystic fibrosis is an inherited chronic disease that affects the lungs and digestive system of about 30,000 children and adults in the United States (70,000 worldwide). A defective gene and its protein product cause the body to produce unusually thick, sticky mucus that:
clogs the lungs and leads to life-threatening lung infections; andobstructs the pancreas and stops natural enzymes from helping the body break down and absorb food.
In the 1950s, few children with cystic fibrosis lived to attend elementary school. Today, advances in research and medical treatments have further enhanced and extended life for children and adults with CF. Many people with the disease can now expect to live into their 30s, 40s and beyond.
Symptoms of Cystic Fibrosis
People with CF can have a variety of symptoms, including:
very salty-tasting skin;persistent coughing, at times with phlegm;frequent lung infections;wheezing or shortness of breath;poor growth/weight gain in spite of a good appetite; andfrequent greasy, bulky stools or difficulty in bowel movements.
About 1,000 new cases of cystic fibrosis are diagnosed each year.More than 70% of patients are diagnosed by age two.More than 45% of the CF patient population is age 18 or older.The predicted median age of survival for a person with CF is in the early 40s.
The Cystic Fibrosis Foundation
Since 1955, the Cystic Fibrosis Foundation has been the driving force behind the pursuit of a cure. Thanks to the dedication and financial backing of our supporters — patients, families and friends, clinicians, researchers, volunteers, individual donors, corporations and staff, we are making a difference.